Despite the impressive win in Dallas, I still don't see us beating San Francisco. Our offensive line is still our weak link and, although it's been our guards and center who seem to be slacking, I don't believe our tackles will be able to pick up SF's pass rush. Also, even though we had a phenomenal game on the ground against Dallas, 1 game alone is not enough to convince me our OL and run game are up to par. Without establishing the running game, Brees has to hold the ball longer but, with SF's pass rush, he'll have to dump it-off. So if we win I see it being on the screen pass which ultimately opens up some deep shots. However, if Vaccaro is out and Harper is left to cover the mid field-well, we already know how that goes. Bush, Quddus and White will hold their own but I still see the Niner's more mature defense, which is more fundamentally sound, winning out.