Without a doubt, the Saints will be heavy favorites when the Buffalo Bills come calling this weekend, but keeping Drew Brees upright may become a bigger challenge than on most game days.
In his second season as a Bill, defensive end Mario Williams is starting look like he is more worthy of signing the most lucrative defensive player contract in history of six years, $100 million dollars. Actually, nobody is worth that much dough in my opinion, but Williams certainly is currently riding on the high end of what has been an up and down career.
With 10.5 sacks to his credit before even reaching halfway point of the season, Williams ranks second among NFL sack leaders and is coming off AFC Defensive Player of the Week honors for his two sacks and forced fumble in the Bills' 23-21 win over the Miami Dolphins.
The strong pass rush capability of Williams should be the Saints greatest concern Sunday. Especially with the running back duo of Fred Jackson and C.J. Spiller being hobbled by injuries.
Regardless of Williams's performance on Sunday, I expect that the Saints will be able to expose other areas in the Bills game and win easily. If that's the case and offensive tackles Zach Strief and Charles Brown are still able to stop Williams from bringing Brees down on the Superdome turf, then depending on which side Williams lines up they should be considered for NFC Offensive Player of the Week honors.